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Which one of the following, if true, most helps to explain the finding of the nicotine study?

  1. Nicotine interacts with certain receptors in the brain causing cognitive changes

  2. The nicotine study included a diverse group of participants

  3. The nicotine consumed was in an altered chemical form

  4. Some participants in the study had pre-existing nicotine sensitivity

The correct answer is: Some participants in the study had pre-existing nicotine sensitivity

The correct answer is D because if some participants in the study had pre-existing nicotine sensitivity, it could explain why the study found that people who consumed nicotine showed varying cognitive changes. Those participants with pre-existing sensitivity might have reacted differently to nicotine compared to those without such sensitivity, leading to the observed differences in cognitive changes. Options A, B, and C do not directly address why the study found that nicotine consumption resulted in varying cognitive changes and therefore are not the most helpful in explaining the study's findings.